diff --git a/.gitignore b/.gitignore new file mode 100644 index 0000000..da746ae --- /dev/null +++ b/.gitignore @@ -0,0 +1,6 @@ +*.psd +*.ai +*.tiff +*.png +*.jpg +*.pdf diff --git a/2016-11-21-basal-ganglia-circuits.dot b/2016-11-21-basal-ganglia-circuits.dot new file mode 100644 index 0000000..2fe0347 --- /dev/null +++ b/2016-11-21-basal-ganglia-circuits.dot @@ -0,0 +1,28 @@ +digraph g { + //node [shape=plaintext]; + node [fontname="sans-serif"]; + edge [arrowhead="o" fontsize=11.0 fontname="sans-serif"] + + ctx [label="cerebral cortex"] + p [label="putamen"] + gpi [label="GP interna"] + gpe [label="GP externa"] + thal [label="VA/VL thalamus"] + snc [label="substantia nigra pars compacta"] + stn [label="subthalmic nucleus"] + + // direct pathway and common + ctx -> p [label="(+) glutamate"] + p -> gpi [label="(-) GABA" arrowhead="dot"] + gpi -> thal [label="(-) GABA" arrowhead="dot"] + thal -> ctx [label="(+) glutamate"] + snc -> p [label="(+) dopamine"] + + // indirect pathway + p -> gpe [label="(-) GABA" arrowhead="dot"] + gpe -> stn [label="(-) GABA" arrowhead="dot"] + stn -> gpi [label="(+) glutamate"] + //stn -> gpi [label="disease: + //hemiballismus" style="dotted" color="red"] //hemiballismus disease + snc -> p [label="(-) dopamine" arrowhead="dot"] +} diff --git a/2016-11-21-basal-ganglia-circuits.svg b/2016-11-21-basal-ganglia-circuits.svg new file mode 100644 index 0000000..b3fb7a7 --- /dev/null +++ b/2016-11-21-basal-ganglia-circuits.svg @@ -0,0 +1,102 @@ + + + + + + +g + + +ctx + +cerebral cortex + + +p + +putamen + + +ctx->p + + +(+) glutamate + + +gpi + +GP interna + + +p->gpi + + +(-) GABA + + +gpe + +GP externa + + +p->gpe + + +(-) GABA + + +thal + +VA/VL thalamus + + +gpi->thal + + +(-) GABA + + +stn + +subthalmic nucleus + + +gpe->stn + + +(-) GABA + + +thal->ctx + + +(+) glutamate + + +snc + +substantia nigra pars compacta + + +snc->p + + +(+) dopamine + + +snc->p + + +(-) dopamine + + +stn->gpi + + +(+) glutamate + + + diff --git a/lipid_bilayer.svg b/lipid_bilayer.svg new file mode 100644 index 0000000..7ae5fc0 --- /dev/null +++ b/lipid_bilayer.svg @@ -0,0 +1,1444 @@ + + + + + + + + + + image/svg+xml + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + closed + open + extracellular + intracellular + + diff --git a/orbitofrontal-cortex-pathways.svg b/orbitofrontal-cortex-pathways.svg new file mode 100644 index 0000000..d5d85b3 --- /dev/null +++ b/orbitofrontal-cortex-pathways.svg @@ -0,0 +1,294 @@ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + V4 + + + + + + + inferior temporal cortex (ventral stream) + + + + + + + + + + + + + thalamus (VPM) + + + + + + + olfactorybulb + + + + + + + thalamus(VPM) + + + + + + + primarysomatosensorycortex + + + + + + + primaryolfactorycortex + + + + + + + primarygustatory cortex + + + + + + + orbitofrontalcortex + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + taste + + + + + vision + + + + + olfaction + + + + + touch + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + \ No newline at end of file diff --git a/vis_connections.svg b/vis_connections.svg new file mode 100644 index 0000000..f9ce0ec --- /dev/null +++ b/vis_connections.svg @@ -0,0 +1,3 @@ + + + Produced by OmniGraffle 6.5.1 2016-11-14 23:25:24 +0000Canvas 1Layer 1TEa/36p/PORECT/LECALLMPPCV1AMPMM2RSACg1PCg2 (FEF)LIM1S1MECHp